Alexandra Misci Hudecova

Dr. Alexandra Misci Hudecova is a research scientist at NILU in the department of Environmental Chemistry and Health Effects with expertise in genetic toxicology, environmental health, and cellular biology. In addition to her academic research, Alexandra has professional experience in Good Laboratory Practice (GLP), working as a Quality Assurance (QA) manager. At NILU’s Health Effects Laboratory, which operates under GLP certification, she contributes to maintaining regulatory compliance, ensuring data integrity, and upholding rigorous laboratory quality standards. This experience has reinforced her commitment to high-quality, reproducible scientific research aligned with international regulatory frameworks. Alexandra is also trained in Safe and Sustainable by Design (SSbD) principles, further supporting her commitment to responsible innovation and environmentally conscious research.

Alexandra earned her PhD studying the effects of Gentiana asclepiadea (willow gentian) extracts and silver nanoparticles on DNA damage/repair, adaptive responses, oxidative stress, antioxidant activity, and related cellular mechanisms in mammalian and human cells. Using a range of in vitro methods, she investigated oxidative DNA damage and cellular defense mechanisms, advancing knowledge on how natural compounds and nanomaterials interact with genomic stability and cellular defense systems.

Prior to joining NILU, Alexandra was a postdoctoral researcher at the Norwegian University of Life Sciences (NMBU) in Oslo. Her work focused on the impact of persistent organic pollutants (POPs) on mice, including gene expression and behavioral studies. She explored neurodevelopmental and epigenetic consequences of maternal exposure to POPs, providing insights into strain-specific responses and maternal exposure outcomes with implications for environmental risk assessment.