{"id":118915,"date":"2026-09-11T21:49:32","date_gmt":"2026-09-11T19:49:32","guid":{"rendered":"https:\/\/nilu.gnist.dev\/publikasjoner\/organohalogenated-contaminants-in-white-tailed-eagle-haliaeetus-albicilla-nestlings-an-assessment-of-relationships-to-immunoglobulin-levels-telomeres-and-oxidative-stress\/"},"modified":"2026-09-11T21:49:32","modified_gmt":"2026-09-11T19:49:32","slug":"organohalogenated-contaminants-in-white-tailed-eagle-haliaeetus-albicilla-nestlings-an-assessment-of-relationships-to-immunoglobulin-levels-telomeres-and-oxidative-stress","status":"publish","type":"nva_publication","link":"https:\/\/nilu.gnist.dev\/en\/publications\/organohalogenated-contaminants-in-white-tailed-eagle-haliaeetus-albicilla-nestlings-an-assessment-of-relationships-to-immunoglobulin-levels-telomeres-and-oxidative-stress\/","title":{"rendered":"Organohalogenated contaminants in white-tailed eagle (Haliaeetus albicilla) nestlings: An assessment of relationships to immunoglobulin levels, telomeres and oxidative stress"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Biomagnifying organohalogenated compounds (OHCs)may have adverse effects on the health of birds, especially<br \/>\nmarine avian top predators that accumulate high OHC loads. Contaminants may impair the humoral immunity<br \/>\nand also influence the antioxidant enzyme activity (i.e. oxidative stress). Moreover, physical conditions and<br \/>\noxidative stress during development may reduce telomere lengths, one of the main mechanisms explaining<br \/>\ncell senescence. To examine the potential effects of environmental contaminants on physiological biomarkers<br \/>\nof health, OHCs with different \u2018physicochemical\u2019 properties were related to immunoglobulin Y levels (IgY; humoral<br \/>\nimmunity), superoxide dismutase enzyme(SOD) activity in blood plasma, and telomere length (measured<br \/>\nin red blood cells) in individual 7\u20138 weeks old nestlings (n = 35) of white-tailed eagles (Haliaeetus albicilla) in<br \/>\nthe Norwegian Sub-Arctic. Different organochlorines (OCs) and perfluoroalkylated substances (PFASs) were<br \/>\nmeasured in blood plasma of nestlings, demonstrating higher concentrations of the emerging contaminants<br \/>\n(PFASs), notably perfluorooctane sulfonate (PFOS), compared to legacy OCs. There were no relationships<br \/>\nbetween the contaminant loads and plasma IgY levels. Moreover, differences between years were found for<br \/>\ntelomere lengths, but this was not related to contaminants and more likely a result of different developmental<br \/>\nconditions. However, therewere significant and negative relationships between the OC loadings and the SOD activity.<br \/>\nThis suggests that some legacy OCs challenge the antioxidant capacity in nestlings of white-tailed eagles.<br \/>\n\u00a9 2015 Elsevier B.V. All rights reserved.<br \/>\nWhite-tailed eagle<br \/>\nPerfluoroalkyl substances<br \/>\nOrganochlorines<br \/>\nOxidative stress<br \/>\nPlasma immunoglobulin Y<br \/>\nTelomeres<\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_id":"","_status":"PUBLISHED","_sync_date":"2026-09-11 14:48:37","footnotes":""},"nva_tax_category":[1099],"class_list":["post-118915","nva_publication","type-nva_publication","status-publish","hentry","nva_tax_category-scientific-journal-publication"],"acf":[],"_links":{"self":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/118915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication"}],"about":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/types\/nva_publication"}],"version-history":[{"count":0,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/118915\/revisions"}],"wp:attachment":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/media?parent=118915"}],"wp:term":[{"taxonomy":"nva_tax_category","embeddable":true,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_tax_category?post=118915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}