{"id":118958,"date":"2026-09-11T21:49:38","date_gmt":"2026-09-11T19:49:38","guid":{"rendered":"https:\/\/nilu.gnist.dev\/publikasjoner\/dna-double%e2%80%90strand-breaks-in-arctic-char-salvelinus-alpinus-from-bjornoya-in-the-norwegian-arctic\/"},"modified":"2026-09-11T21:49:38","modified_gmt":"2026-09-11T19:49:38","slug":"dna-double%e2%80%90strand-breaks-in-arctic-char-salvelinus-alpinus-from-bjornoya-in-the-norwegian-arctic","status":"publish","type":"nva_publication","link":"https:\/\/nilu.gnist.dev\/en\/publications\/dna-double%e2%80%90strand-breaks-in-arctic-char-salvelinus-alpinus-from-bjornoya-in-the-norwegian-arctic\/","title":{"rendered":"DNA double\u2010strand breaks in Arctic char (Salvelinus alpinus) from Bj\u00f8rn\u00f8ya in the Norwegian Arctic"},"content":{"rendered":"<p class=\"wp-block-paragraph\">High levels of organochlorine contaminants (OCs) have been found in arctic char (Salvelinus alpinus) from Lake Ellasj\u00f8en, Bj\u00f8rn\u00f8ya (Norwegian Arctic). The aim of the present study was to investigate the potential genotoxic effect of environmental organochlorine contaminant exposure in arctic char from Ellasj\u00f8en compared with arctic char from the low\u2010contaminated Lake Laksvatn nearby. Blood was analyzed using agarose gel electrophoresis and image data analysis to quantify the fraction of total DNA that migrated into the gel (DNA\u2010FTM) as a relative measure of DNA double\u2010strand breaks (DSBs). Analysis by GC\u2010MS of muscle samples showed an average 43 times higher concentration of \u03a3OCs in arctic char from Ellasj\u00f8en (n = 18) compared with Laksvatn char (n = 21). Char from Lake Ellasj\u00f8en had a much higher frequency of DSBs, as measured by DNA\u2010FTM, than char from Lake Laksvatn. Principal component analysis and multiple linear regressions show that there was a significant positive relationship between DSBs and levels of organochlorine contaminants in the char. In addition, DSBs were less frequent in reproductively mature char than in immature char. The results suggest that organochlorine contaminants are genotoxic to arctic char.<\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_id":"","_status":"PUBLISHED","_sync_date":"2026-09-11 14:48:43","footnotes":""},"nva_tax_category":[1099],"class_list":["post-118958","nva_publication","type-nva_publication","status-publish","hentry","nva_tax_category-scientific-journal-publication"],"acf":[],"_links":{"self":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/118958","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication"}],"about":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/types\/nva_publication"}],"version-history":[{"count":0,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/118958\/revisions"}],"wp:attachment":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/media?parent=118958"}],"wp:term":[{"taxonomy":"nva_tax_category","embeddable":true,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_tax_category?post=118958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}