{"id":92554,"date":"2026-06-29T14:36:56","date_gmt":"2026-06-29T12:36:56","guid":{"rendered":""},"modified":"2026-06-29T14:46:44","modified_gmt":"2026-06-29T12:46:44","slug":"0198cc452168-9ccd3ae5-bbaf-4add-b651-9e89d463e8a5","status":"publish","type":"nva_publication","link":"https:\/\/nilu.gnist.dev\/en\/publications\/0198cc452168-9ccd3ae5-bbaf-4add-b651-9e89d463e8a5\/","title":{"rendered":"Identification of several Tonalide (R) transformation products in the environment"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Organic synthesis combined with trace-analytical methods has been applied to detect potential Tonalide (AHTN) transformation products in a semi-quantitative way in environmental samples by using a well-established trace-analytical method, developed for the quantification of the parent compound AHTN. For the first time, indications for the presence of transformation products of the synthetic musk compound 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)ethanone (1) (Tonalide\u00ae, AHTN) have been found in the environment. Pure standards of the detected products were obtained by multistep syntheses from Tonalide\u00ae. Two main derivatives, 3-acetyl-5,6,7,8-tetrahydro-5,5,7,8,8-pentamethyl-2-naphthalenecarbaldehyde (2) and (3-ethyl-5,6,7,8-tetrahydro-5,5,7,8,8-pentamethyl-2-naphthalenyl)methanol (4), and three minor products, (5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphtalenyl)methanol (6), 5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphtalenecarbaldehyde (7), and methyl 5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenecarboxylate (8), were identified in three human breast-milk samples and three fish samples. All samples contained one or several of these transformation products at a concentration range of around 10 pg\/g wet weight.<\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_id":"","_status":"PUBLISHED","_sync_date":"2026-06-29 14:36:56","footnotes":""},"nva_tax_category":[1059],"class_list":["post-92554","nva_publication","type-nva_publication","status-publish","hentry","nva_tax_category-scientific-journal-publication"],"acf":[],"_links":{"self":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/92554","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication"}],"about":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/types\/nva_publication"}],"version-history":[{"count":1,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/92554\/revisions"}],"predecessor-version":[{"id":92555,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_publication\/92554\/revisions\/92555"}],"wp:attachment":[{"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/media?parent=92554"}],"wp:term":[{"taxonomy":"nva_tax_category","embeddable":true,"href":"https:\/\/nilu.gnist.dev\/en\/wp-json\/wp\/v2\/nva_tax_category?post=92554"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}