Preventing regrettable substitutions: a proposal for a tiered testing approach for BPA alternatives under the PARC initiative
Frontiers in Toxicology
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Miljøkjemi og helse
Kjeller
ney@nilu.no
Dr. Naouale El Yamani er seniorforsker ved NILUs helseeffektlaboratorium. Forskningen hennes knytter sammen kjemikaliesikkerhet, menneskers helse og tryggere innovasjon. Med ekspertise innen genetisk toksikologi, nanotoksikologi og human biomonitorering kombinerer hun eksperimentelle data, biomarkører, eksponeringsinformasjon og statistiske analyser for å forstå mulige helseeffekter og støtte beslutninger om kjemikaliesikkerhet. Arbeidet hennes bidrar til å utvikle og ta i bruk nye tilnærmingsmetoder (New Approach Methodologies, NAMs) og integrere dem med beregningsbaserte tilnærminger, read-across og mekanistisk forståelse i neste generasjons risikovurdering (NGRA).
Med bred forståelse av regulatoriske behov og erfaring med OECDs retningslinjer for testing, metodeutvikling og kvalitetssikring i henhold til god laboratoriepraksis (GLP) bidrar hun til å fremskaffe og vurdere pålitelig kunnskapsgrunnlag som er relevant for regulatoriske vurderinger. Dette omfatter vurdering av studiekvalitet, biologisk relevans og usikkerhet for å identifisere nye bekymringer og kunnskapshull.
Hun leder tverrfaglig forskning som kobler kjemikaliesikkerhet, trygge og bærekraftige løsninger gjennom design (Safe and Sustainable by Design, SSbD) og sirkulær økonomi. Gjennom dette arbeidet omsetter hun vitenskapelig kunnskap til praktisk veiledning for tryggere kjemikalier, materialer og produkter.
Frontiers in Toxicology
Safe and Sustainable Value Creation by Design
Genotoxicity Assessment. Methods and Protocols
Environment International
Colloids and Surfaces B: Biointerfaces
Toxicology Letters
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Mutagenesis
Computational and Structural Biotechnology Journal
EFSA Supporting publication
iScience
Nano Today
Nature Protocols
Critical Reviews in Toxicology
Bioelectrochemistry
Frontiers in Toxicology
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Mutagenesis
Frontiers in Toxicology
Frontiers in Toxicology
Frontiers in Toxicology
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Nano Today
Nanotoxicology in Safety Assessment of Nanomaterials
Biomedicine & Pharmacotherapy
Nature Nanotechnology
Chemical Research in Toxicology
Computational and Structural Biotechnology Journal
Nanomaterials
Cancers
Nanomaterials
Nanotoxicity
DNA Repair
European Journal of Nutrition
Water environment research
Free Radical Biology & Medicine
International Journal of Pharmaceutics
Food and Chemical Toxicology (FCT)
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Mutagenesis
Science of the Total Environment
Journal of Micro and Nano-Manufacturing
The Comet Assay in Toxicology. 2nd Edition.
Environmental Research
Mutagenesis
Neoplasma (Bratislava)
Toxicology Letters
Food and Chemical Toxicology (FCT)
Particle and Fibre Toxicology
Mutagenesis
Genotoxicity and DNA repair. A practical approach
SSbD25 Conference
International Congress of Toxicology ICT2025
SETAC Europe 35th Annual Meeting
NSFT Winter Meeting
NSFT Winter Meeting (Beitostølen)
22nd Global Conference on Sustainable Manufacturing
NSFT Winter Meeting
SSbD25 Conference
EFSA Journal
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
52nd EEMGS Meeting
52nd EEMGS Meeting
Joint International Scientific Conference VISION and International Network of Young Scientists Conference
International Conference on New Achievements in Science, Technology and Arts (ICNA-STA)
Conference on Tools and Tests for Safer-by-Design Nanomaterials
Nature Protocols
Inhaled Particles and NanOEH Conference 2023
Joint International Scientific Conference VISION and International Network of Young Scientists Conference
PARC Workshop
Annals of Work Exposures and Health
NanoWeek
NanoWeek
Joint EEMGS meeting & International Comet Assay Workshop
Advances in Experimental Medicine and Biology
Environmental and Molecular Mutagenesis
Toxicology Letters
Toxicology Letters
Toxicology Letters
Toxicology Letters
NanoTox 2018
Toxicology Letters
39th ESPEN Congress 2017
Internationa conference in Nanotoxicology
iLCA4SSbD aims to accelerate the industrial uptake of Lifecycle Assessment (LCA) in Safe and Sustainable by Design (SSbD) by developing a user-friendly digital platform that supports integrated LCA (iLCA) and […]
Surface coatings are essential for protecting materials in demanding and harsh environments. However, many of them are fossil-based, which contributes considerably to energy consumption and climate change through GHG emissions. […]
PARC is a very large EU-funded project with almost 200 partners in 28 countries running in the period 2021 – 2027. The project is coordinated by ANSES, the French Agency […]
PARC is an EU-wide research and innovation partnership programme to support EU and national chemical risk assessment and risk management bodies with new data, knowledge, methods, networks and skills to […]
ANALYST har som mål å akselerere overgangen mot en tryggere og mer bærekraftig industriell verdikjede, samtidig som prosjektet fremmer og utvider den eksisterende kunnskapen om Safe and Sustainable by Design […]
The unique properties of nanomaterials (NMs), relative to their bulk form, has seen them used in a rapidly increasing number of commercial applications. However, with these useful new properties of […]
PROPLANET tar for seg nye løsninger for beleggsmaterialer, med en tilnærming som kombinerer bærekraftige forretningsmodeller og teknologisk innovasjon. Målet er å overvinne barrierer innen miljøvern, sikkerhet, kjemiske forbedringer og etablering […]
This project aims to develop the strategic roadmap in response to the tender “Development of a roadmap for action for the project: Advancing aggregate exposure to chemicals in EU” (hereafter […]
This project aims at the development of a new type of LSCD treatment using advanced therapy medicinalproducts (ATMP). It is a direct continuation of a previous research project of the […]
Frontiers in Toxicology
Safe and Sustainable Value Creation by Design
Genotoxicity Assessment. Methods and Protocols
Environment International
Colloids and Surfaces B: Biointerfaces
Toxicology Letters
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Mutagenesis
Computational and Structural Biotechnology Journal
EFSA Supporting publication
iScience
Nano Today
Nature Protocols
Critical Reviews in Toxicology
Bioelectrochemistry
Frontiers in Toxicology
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Mutagenesis
Frontiers in Toxicology
Frontiers in Toxicology
Frontiers in Toxicology
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Nano Today
Nanotoxicology in Safety Assessment of Nanomaterials
Biomedicine & Pharmacotherapy
Nature Nanotechnology
Chemical Research in Toxicology
Computational and Structural Biotechnology Journal
Nanomaterials
Cancers
Nanomaterials
Nanotoxicity
DNA Repair
European Journal of Nutrition
Water environment research
Free Radical Biology & Medicine
International Journal of Pharmaceutics
Food and Chemical Toxicology (FCT)
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Mutagenesis
Science of the Total Environment
Journal of Micro and Nano-Manufacturing
The Comet Assay in Toxicology. 2nd Edition.
Environmental Research
Mutagenesis
Neoplasma (Bratislava)
Toxicology Letters
Food and Chemical Toxicology (FCT)
Particle and Fibre Toxicology
Mutagenesis
Genotoxicity and DNA repair. A practical approach
SSbD25 Conference
International Congress of Toxicology ICT2025
SETAC Europe 35th Annual Meeting
NSFT Winter Meeting
NSFT Winter Meeting (Beitostølen)
22nd Global Conference on Sustainable Manufacturing
NSFT Winter Meeting
SSbD25 Conference
EFSA Journal
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
52nd EEMGS Meeting
52nd EEMGS Meeting
Joint International Scientific Conference VISION and International Network of Young Scientists Conference
International Conference on New Achievements in Science, Technology and Arts (ICNA-STA)
Conference on Tools and Tests for Safer-by-Design Nanomaterials
Nature Protocols
Inhaled Particles and NanOEH Conference 2023
Joint International Scientific Conference VISION and International Network of Young Scientists Conference
PARC Workshop
Annals of Work Exposures and Health
NanoWeek
NanoWeek
Joint EEMGS meeting & International Comet Assay Workshop
Advances in Experimental Medicine and Biology
Environmental and Molecular Mutagenesis
Toxicology Letters
Toxicology Letters
Toxicology Letters
Toxicology Letters
NanoTox 2018
Toxicology Letters
39th ESPEN Congress 2017
Internationa conference in Nanotoxicology
iLCA4SSbD aims to accelerate the industrial uptake of Lifecycle Assessment (LCA) in Safe and Sustainable by Design (SSbD) by developing a user-friendly digital platform that supports integrated LCA (iLCA) and […]
Surface coatings are essential for protecting materials in demanding and harsh environments. However, many of them are fossil-based, which contributes considerably to energy consumption and climate change through GHG emissions. […]
PARC is a very large EU-funded project with almost 200 partners in 28 countries running in the period 2021 – 2027. The project is coordinated by ANSES, the French Agency […]
PARC is an EU-wide research and innovation partnership programme to support EU and national chemical risk assessment and risk management bodies with new data, knowledge, methods, networks and skills to […]
ANALYST har som mål å akselerere overgangen mot en tryggere og mer bærekraftig industriell verdikjede, samtidig som prosjektet fremmer og utvider den eksisterende kunnskapen om Safe and Sustainable by Design […]
The unique properties of nanomaterials (NMs), relative to their bulk form, has seen them used in a rapidly increasing number of commercial applications. However, with these useful new properties of […]
PROPLANET tar for seg nye løsninger for beleggsmaterialer, med en tilnærming som kombinerer bærekraftige forretningsmodeller og teknologisk innovasjon. Målet er å overvinne barrierer innen miljøvern, sikkerhet, kjemiske forbedringer og etablering […]
This project aims to develop the strategic roadmap in response to the tender “Development of a roadmap for action for the project: Advancing aggregate exposure to chemicals in EU” (hereafter […]
This project aims at the development of a new type of LSCD treatment using advanced therapy medicinalproducts (ATMP). It is a direct continuation of a previous research project of the […]