Publikasjoner

FAIRMODE 2017-2019 roadmap.

Thunis, P.; Belis, C.; Henrichs, T.; Hoss, F.; Ortiz, A. G.; Janssen S.; Guerreiro, C.; Tarrasón, L.; Guevara, M.; Pirovano, G.; Clappier, A.; Monteiro, A.

FAIRiCUBE: Enabling Gridded Data Analysis for All

FACTS: Preliminary results

Factors associated with maternal serum levels of perfluoroalkyl substances and organochlorines: A descriptive study of parous women in Norway and Sweden.

Lauritzen, H.B.; Larose, T.L.; Øien, T.; Odland, J.Ø.; van de Bor, M.; Jacobsen, G.W.; Sandanger, T.

Factors affecting bioaccumulation of cyclic volatile methyl siloxanes in a subarctic benthopelagic food web.

Krogseth, I. S.; Undeman, E.; Evenset, A.; Christensen, G. N.; Whelan, M. J.; Breivik, K.; Evenset, A.; Warner, N. A.

Facilitating knowledge transfer: decision support tools in environment and health.

Liu, H.-Y.; Bartonova, A.; Neofytou, P.; Yang, A.; Kobernus, M.J.; Negrenti, E.; Housiadas, C.

Eyjafjallajokull volcanic ash concentrations determined from CALIOP and SEVIRI measurements. NILU F

Prata, F.

Extremt varmt i stan? Köp en vit bil

Muri, Helene (intervjuobjekt)

Global uppvärmning och extremvärme i städerna är ett växande problem. Nu lanserar forskarna en ny och helt oväntad lösning.

Extreme stratospheric vortex events in the ECMWF seasonal forecast model with re-analyses

Extreme precipitation events over north China in August 2010 and their link to eastward-propagating wave-trains across Eurasia: observations and monthly forecasting.

Orsolini, Y. J.; Zhang, L.; Peters, D. H. W.; Fraedrich, K.; Zhu, X.; Schneidereit, A.; van den Hurk, B.

Extreme precipitation event over North China in August 2010: observations, monthly forecasting, and link to intra-seasonal variability of the Silk-Road wave-train across Eurasia.

Orsolini, Y.; Zhang, L.; Peters, D.; Fraedrich, K.

Extreme climate of the global troposphere and stratosphere in the 1940-42 related to El Nino.

Brönnimann, S.; Luterbacher, J.; Staehelin, J.; Svendby, T. M.; Hansen, G.; Svenøe, T.

Extracellular Vesicles as Next-Generation Diagnostics and Advanced Therapy Medicinal Products

Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and therapeutic modalities. This paper describes major GMP-based upstream and downstream manufacturing processes for EV large-scale production, also focusing on post-processing technologies such as surface bioengineering and uploading studies to yield novel EV-based diagnostics and advanced therapy medicinal products. This paper also focuses on the quality, safety, and efficacy issues of the bioengineered EV drug candidates before first-in-human studies. Because clinical trials involving extracellular vesicles are on the global rise, this paper encompasses different clinical studies registered on clinical-trial register platforms, with varying levels of advancement, highlighting the growing interest in EV-related clinical programs. Navigating the regulatory affairs of EVs poses real challenges, and obtaining marketing authorization for EV-based medicines remains complex due to the lack of specific regulatory guidelines for such novel products. This paper discusses the state-of-the-art regulatory knowledge to date on EV-based diagnostics and medicinal products, highlighting further research and global regulatory needs for the safe and reliable implementation of bioengineered EVs as diagnostic and therapeutic tools in clinical settings. Post-marketing pharmacovigilance for EV-based medicinal products is also presented, mainly addressing such topics as risk assessment and risk management.