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Extensive release of methane from Arctic seabed west of Svalbard during summer 2014 does not influence the atmosphere.

Myhre, C.L.; Ferré, B.; Platt, S.M.; Silyakova, A.; Hermansen, O.; Allen, G.; Pisso, I.; Schmidbauer, N.; Stohl, A.; Pitt, J.; Jansson, P.; Greinert, J.; Percival, C.; Fjaeraa, A.M.; O'Shea, S.J.; Gallagher, M.; Le Breton, M.; Bower, K.N.; Bauguitte, S.J.B.; Dalsøren, S.; Vadakkepuliyambatta, S.; Fisher, R.E.; Nisbet, E.G.; Lowry, D.; Myhre, G.; Pyle, J.A.; Cain, M.; Mienert, J.

2016

Expression of DNA repair genes in arctic char (Salvelinus alpinus) from Bjørnøya in the Norwegian Arctic

High levels of organochlorines (OCs) have been measured in arctic char (Salvelinus alpinus) from Lake Ellasjøen on Bjørnøya, Norway (74.30°N, 19.0°E). In a nearby lake, Laksvatn, the OC-levels in arctic char were low. A previous study has shown that char from Ellasjøen had significantly higher levels of DNA double strand breaks (DSBs) than char from Lake Laksvatn. Even though there is increasing evidence of the genotoxic effects of OCs, little is known about the effects of OCs on the DNA repair system. The aim of the present study was to determine if the two main DNA DSB repair mechanisms, homologous recombination (HR) and non-homologous end-joining (NHEJ), are affected by the higher OC and DSB level in char from Ellasjøen. This was analysed by comparing the transcript level of 11 genes involved in DNA DSB repair in char liver samples from Ellasjøen (n = 9) with char from Laksvatn (n = 12). Six of the investigated genes were significantly upregulated in char from Ellasjøen. As the expression of DNA DSB repair genes was increased in the contaminant-exposed char, it is likely that the DNA DSB repair capacity is induced in these individuals. This induction was positively correlated with the DNA DSB and negatively correlated with one or several OCs for four of these genes. However, the strongest predictor variable for DNA repair genes was habitat, indicating genetic differences in repair capacity between populations. As char from Ellasjøen still had significantly higher levels of DSBs compared to char from Laksvatn, it is possible that chronic exposure to OCs and continued production of DSB has caused selective pressure within the population for fixation of adaptive alleles. It is also possible that DSB production was exceeding the repair capacity given the prevailing conditions, or that the OC or DSB level was above the threshold value of inhibition of the DNA repair system resulting in the rate of DNA damage exceeding the rate of repair.

2021

Exposures in Indoor Air Affecting Health

Indoor air quality (IAQ) is influenced by a wide range of chemical, biological and physical agents that can negatively impact physical, immunological and mental health. Adverse health effects depend on the type and concentration of pollutants, duration of exposure, and individual susceptibility. The availability of data on IAQ is limited, as are standardized approaches for evaluating its health impact. This expert review aims to describe the most important indoor air determinants affecting health, and present the IDEAL cluster, which comprises seven EU‐funded scientific projects on the topic of IAQ and human health. Across the IDEAL projects, knowledge is generated on exposure to a wide range of indoor air pollutants, including well‐known hazards and more explorative chemical and microbiological determinants. The projects will also contribute to the implementation of low‐cost and/or real‐time sensors on IAQ, as well as advanced chemical and microbiological analyses, and evaluate various interventions to improve IAQ. Several of them focus on particularly vulnerable groups. Raising public awareness and implementing measures to reduce pollutant levels are essential for safeguarding health, particularly in urban areas with elevated pollution levels.

2026

Exposure to PFAS is associated with telomere length dynamics and demographic responses of an arctic top predator

Environmental factors that can influence telomeres are diverse, but the association between telomeres and exposure to environmental contaminants is yet to be elucidated. To date, prior studies have focused on legacy persistent chlorinated pollutants (POPs), while the effects of poly- and perfluoroalkyl substances (PFAS) have been poorly documented. Here, we investigated the associations among PFAS congeners, absolute telomere length (cross-sectional approach), and telomere dynamics (rate of telomere length change over time, longitudinal approach) in one of the most contaminated arctic top predators, the glaucous gull Larus hyperboreus from Svalbard. We further estimated the effect of PFAS on apparent survival rates and re-sighting probabilities using a 10-year capture/recapture dataset (2010–2019). We found that birds exposed to higher concentrations of perfluorononadecanoate (PFNA) (median of 1565 pg/mL of ww in males and 1370 pg/mL of ww in females) and perfluorotetradecanoate (PFTeDA) (median of 370 pg/mL of ww in males and 210 pg/mL of ww in females) showed the slowest rate of telomere shortening. We also found that high blood concentrations of perfluorooctanoate (PFOA) (median of 120 pg/mL of ww in males and 150 pg/mL of ww in females) and perfluorohexanesulfonate (PFHxS) (median of 495 pg/mL of ww in males and 395 pg/mL of ww in females) were positively associated with higher re-sighting probabilities and apparent survival in males but not in females. Our work is the first to report an association between single PFAS compounds and telomeres, and the first to link PFAS exposure with survival probabilities, suggesting that the effect of PFAS exposure might be more tied to the type of compound rather than the total concentration of PFAS.

2020

Exposure to oxychlordane is associated with shorter telomeres in arctic breeding kittiwakes.

Blevin, P.; Angelier, F.; Tartu, S.; Ruault, S.; Bustamante, P.; Herzke, D.; Moe, B.; Bech, C.; Gabrielsen, G.W.; Bustnes, J.O.; Chastel, O.

2016

Exposure to multiple environmental agents and their effect.

Koppe, J.; Bartonova, A.; Bolte, G.; Bistrup, M.L.; Busby, C.; Butter, M.; Dorfman, P.; Fucic, A.; Gee, D.; Van Den Hazel, P.; Howard, V.; Kohlhuber, M.; Leijs, M.; Lundqvist, C.; Moshammer, H.; Naginiene, R.; Nicolopoulou-Stamati, P.; G.; Wallis, M.; Zuurbier, M.

2006

Exposure scenario approach to environmental health problems: two case studies. NILU F

Bartonova, A.; Liu, H.Y.; Loh, M.; ENVIRISK team.

2011

Exposure risks from pollutants in domestic environments: The urban exposure project.

Coulson, G.; Bartonova, A.; Bøhler, T.; Broday, D.M.; Colbeck, I.; Fløisand, I.; Fudala, J.; Hollander, W.; Housiadas, C.; Lazaridis, M.; Smolik, J.

2005

Exposure of children to particulate matter in urban areas - model calculations.

Fløisand, I.; Mc Innes, H.; Broday, D.; Lützenkirchen, S.; Holländer, W.; Bartonova, A.

2006

Exposure of children and adults to particulate matter in urban areas - model calculations. NILU PP

Fløisand, I.; Mc Innes, H.; Broday, D.; Lützenkirchen, S.; Holländer, W.; Bartonova, A.; Jablonska, H.T.B.

2007

Exposure maps for two megacities within the MEGAPOLI project.

Soares, J.; Karppinen, A.; Kukkonen, J.; Denby, B.; Finard, S.; Cassiani, M.; Radice, P.

2011

Exposure assessment with the urban exposure management tool - case study Oslo.

Lützenkirchen, S.; Laupsa, H.; Fløisand, I.; Bøhler, T.; Hollander, W.; Broday, D.M.

2006

Exposure assessment with the urban exposure management tool - case study Oslo.

Lützenkirchen, S.; Laupsa, H.; Fløisand, I.; Bøhler, T.

2006

Exploring the role of sea-ice for seasonal forecasts.

Senan, R.; Benestad, R.E.; Balmaseda, M.; Ferranti, L.; Orsolini, Y.J.; Melsom, A.

2009

Exploring the relationship between the Arctic sea-ice and mid to high latitude circulation anomalies. NILU PP

Benestad, R.E.; Senan, R.; Balmaseda, M.A.; Ferranti, L.; Orsolini, Y.J.; Melsom, A.

2009

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